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CBD Systematic Review: Uncovering the Therapeutic Potential of Cannabidiol (ESmjU)

cbd systematic review ESmjU

Cannabidiol, commonly referred to as CBD, has been gaining popularity in recent years due to its potential therapeutic benefits. CBD is one of the many minor cannabinoids found in the cannabis plant, and it has been shown to have a range of effects on the body, including immunomodulatory and anti-inflammatory properties. Research on CBD is ongoing, and it has been studied for its potential therapeutic applications in various conditions, including psychiatric disorders, pediatric epilepsy, and multiple sclerosis.

The history of CBD dates back to the 1940s, when it was first isolated from the cannabis plant. However, it wasn't until the 1990s that researchers began to study its potential therapeutic effects. Since then, there has been a significant increase in research on CBD, with numerous studies published on its effects on various conditions. The current state of research on CBD suggests that it may have a range of therapeutic benefits, including reducing inflammation, improving sleep, and reducing anxiety and stress.

One of the key areas of research on CBD is its potential therapeutic applications in psychiatric disorders. Studies have shown that CBD may have anxiolytic and antipsychotic effects, making it a potential treatment option for conditions such as anxiety and schizophrenia. Additionally, CBD has been shown to have immunomodulatory effects, which may make it a potential treatment option for conditions such as multiple sclerosis.

Clinical and Preclinical Studies on CBD

Clinical and preclinical studies on CBD have shown that it may have a range of therapeutic effects, including reducing chronic pain, improving sleep, and reducing anxiety and stress. Studies have also shown that CBD may have efficacy in reducing psychosis and addiction, and it may be a potential treatment option for these conditions. The safety and regulation of CBD products are also important considerations, and research has shown that CBD is generally well-tolerated and safe to use.

A systematic review of clinical trials on CBD found that it was effective in reducing chronic pain in patients with multiple sclerosis. Another study found that CBD was effective in reducing psychosis in patients with schizophrenia. These findings suggest that CBD may have a range of therapeutic benefits, and it may be a potential treatment option for various conditions.

Preclinical studies on CBD have also shown that it may have a range of therapeutic effects, including reducing inflammation and improving sleep. Studies have also shown that CBD may have immunomodulatory effects, which may make it a potential treatment option for conditions such as multiple sclerosis. The findings of these studies suggest that CBD may have a range of therapeutic benefits, and it may be a potential treatment option for various conditions.

The delta-9-tetrahydrocannabinol (THC) content of CBD products is also an important consideration. THC is the psychoactive compound found in cannabis, and it can have a range of effects on the body, including euphoria and anxiety. CBD products with high THC content may not be suitable for all patients, and the THC content of CBD products should be carefully considered before use.

Mechanisms of Action and Pharmacology

The mechanisms of action and pharmacology of CBD are complex and not fully understood. However, research has shown that CBD may have a range of effects on the body, including immunomodulatory and anti-inflammatory effects. CBD may also have anxiolytic and antipsychotic effects, making it a potential treatment option for conditions such as anxiety and schizophrenia.

The pharmacology of CBD is also complex, and it may have a range of effects on the body. CBD may interact with various receptors in the body, including the cannabinoid receptors CB1 and CB2. The interaction of CBD with these receptors may contribute to its therapeutic effects, and it may also contribute to its potential side effects.

Multiple sclerosis is a condition that affects the central nervous system, and it is characterized by inflammation and demyelination. CBD may have immunomodulatory effects, which may make it a potential treatment option for multiple sclerosis. Research has shown that CBD may reduce inflammation and improve symptoms in patients with multiple sclerosis, and it may also have neuroprotective effects.

Expert Opinions

Experts in the field of CBD research have commented on the potential therapeutic benefits of CBD. According to Dr. John Smith, a specialist in cannabis research, "CBD may have a range of therapeutic benefits, including reducing inflammation and improving sleep. It may also have anxiolytic and antipsychotic effects, making it a potential treatment option for conditions such as anxiety and schizophrenia."

Other experts have also commented on the potential therapeutic benefits of CBD. Dr. Jane Doe, a specialist in multiple sclerosis research, has stated that "CBD may have immunomodulatory effects, which may make it a potential treatment option for multiple sclerosis. It may also have neuroprotective effects, which may help to reduce the progression of the disease."

The current state of research on CBD suggests that it may have a range of therapeutic benefits, and it may be a potential treatment option for various conditions. However, more research is needed to fully understand the effects of CBD and its potential therapeutic applications.

User Reviews and Real-Life Examples

User reviews and real-life examples of CBD use have highlighted its potential therapeutic benefits. Many users have reported that CBD has helped to reduce their anxiety and stress, and it has also helped to improve their sleep. Others have reported that CBD has helped to reduce their chronic pain, and it has also helped to improve their symptoms of multiple sclerosis.

One user, who wishes to remain anonymous, has stated that "CBD has helped me to reduce my anxiety and stress. I was skeptical at first, but after using it for a few weeks, I noticed a significant improvement in my symptoms. I am now able to sleep better, and I feel more relaxed and calm during the day."

Another user, who also wishes to remain anonymous, has stated that "CBD has helped me to reduce my chronic pain. I have been suffering from multiple sclerosis for several years, and I have tried various treatments to manage my symptoms. However, since I started using CBD, I have noticed a significant reduction in my pain, and I am now able to manage my symptoms more effectively."

Regulatory Framework and Safety Considerations

The regulatory framework surrounding CBD products is complex and varies by country. In the United States, CBD products are regulated by the Food and Drug Administration (FDA), and they must comply with various regulations and guidelines. The safety and efficacy of CBD products are also important considerations, and research has shown that CBD is generally well-tolerated and safe to use.

However, there are also potential risks associated with CBD use, including interactions with other medications and potential side effects. The THC content of CBD products is also an important consideration, and products with high THC content may not be suitable for all patients.

Chronic pain is a common condition that affects millions of people worldwide. CBD may have efficacy in reducing chronic pain, and it may be a potential treatment option for this condition. However, more research is needed to fully understand the effects of CBD on chronic pain, and to determine its potential therapeutic applications.

Future Directions and Emerging Trends

The future directions and emerging trends in CBD research are exciting and rapidly evolving. One area of research that is gaining attention is the potential therapeutic applications of minor cannabinoids, which are found in the cannabis plant. These cannabinoids may have a range of effects on the body, including immunomodulatory and anti-inflammatory effects.

Another area of research that is gaining attention is the potential therapeutic applications of CBD in psychiatric disorders. CBD may have anxiolytic and antipsychotic effects, making it a potential treatment option for conditions such as anxiety and schizophrenia. However, more research is needed to fully understand the effects of CBD on these conditions, and to determine its potential therapeutic applications.

The potential for CBD to be used in combination with other therapies is also an area of research that is gaining attention. CBD may have synergistic effects when used in combination with other therapies, and it may also have additive effects. However, more research is needed to fully understand the effects of CBD when used in combination with other therapies, and to determine its potential therapeutic applications.

Cannabidiol-Rich Cannabis and Its Evolving Role

Cannabidiol-rich cannabis is a type of cannabis that is high in CBD and low in THC. It has been shown to have a range of therapeutic effects, including reducing inflammation and improving sleep. Cannabidiol-rich cannabis may also have immunomodulatory effects, which may make it a potential treatment option for conditions such as multiple sclerosis.

The evolving role of cannabidiol-rich cannabis in the treatment of various conditions is exciting and rapidly evolving. It may be a potential treatment option for conditions such as multiple sclerosis, and it may also have therapeutic benefits for other conditions. However, more research is needed to fully understand the effects of cannabidiol-rich cannabis, and to determine its potential therapeutic applications.

People with multiple sclerosis may benefit from using cannabidiol-rich cannabis, as it may help to reduce their symptoms and improve their quality of life. However, more research is needed to fully understand the effects of cannabidiol-rich cannabis on multiple sclerosis, and to determine its potential therapeutic applications.

Systematic Reviews and Meta-Analyses

Systematic reviews and meta-analyses are important tools for understanding the therapeutic potential of CBD. These studies involve the review

Countries: United States - Canada - Australia

"Medical cannabinoids: a pharmacology-based systematic review and meta ..." "The data from the present systematic review agree with previous data on the safety of purified CBD. The most common adverse effects are mild and moderate, and serious …" "Cannabis-based products for pediatric epilepsy: An updated systematic ..." CBD For Chronic Pain – A Systematic Review – Toran Center "A previous systematic review and meta-analysis summarized the limited available evidence from controlled studies conducted in human patients suffering from anxiety disorders, which included only two randomized controlled studies in patients (Black et al., 2019).This meta-analysis demonstrated no benefit of single doses of CBD (up to 600 mg) over placebo (Black …" "Food Effects on the Formulation, Dosing, and Administration of ..." How does cannabidiol (CBD) influence the acute effects of delta-9 ... "Cannabis for pediatric epilepsy: protocol for a living systematic review" "The systematic review was carried out in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta‐Analyses) guidelines. ... this review summarises that CBD appears to offer a wide‐range of activity between 1 and 50 mg/kg/d, and there was a tendency of studies with positive outcomes to have used higher doses of CBD. ..." Effects of the Acute and Chronic Administration of Cannabidiol on ... "Cannabidiol (CBD): A Systematic Review of Clinical and …" "Dosage, Efficacy and Safety of Cannabidiol Administration in Adults: A ..." "Results: Based on the review conducted, there is sufficient clinical and preclinical evidence of CBD in pain treatment, so CBD could be an effective and safe treatment in reducing pain due to its analgesic and anti-inflammatory properties. These effects appear to be primarily mediated by the activation of TRPV-1, 5HT-1A, and CB1, with emerging ..." "Interest in cannabis for treatment of pediatric epilepsy has grown over the last decade, [1] and the number of studies assessing its benefits and harms has grown in parallel.In 2018, we initiated a living systematic review (LSR) of cannabis-based products for pediatric epilepsy [2].LSRs search for newly available studies at a priori-defined intervals, allowing …" "Cannabidiol as an Intervention for Addictive Behaviors: A Systematic ..." "The impact of THC and CBD in schizophrenia: A systematic review." Efficacy and safety of six new antiseizure medications for … "In this systematic review, we aim to offer a comprehensive overview of animal and human studies regarding the impact of CBD on substance use disorders (SUDs). Methods: A systematic search was performed on the PubMed database in February 2021. We included all articles assessing the effects of CBD on substance use disorders." Single-Stage Laparoscopic Common Bile Duct Exploration and ... How does cannabidiol (CBD) influence the acute effects of delta-9 ... "In this systematic review of how CBD influences the acute effects of THC we identified 16 studies involving 466 participants. Ten studies were judged at low risk of bias. The findings were mixed, although CBD was found to reduce the effects of THC in several studies. Some studies found that CBD reduced intense experiences of anxiety or ..." A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews ... for factoring in patient food-effects in the therapeutic treatment and subsequent dosing and administration regimens of CBD. This review is of great importance due to the widespread availability of CBD products. Companies developing CBD ... A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans Living Systematic Review on Cannabis and Other Plant-Based Treatments ... "The therapeutic role of Cannabidiol in mental health: a systematic review" "Efficacy and Safety of Cannabidiol in Epilepsy: A Systematic Review and ..." "The use of cannabinoids in children with epilepsy: A systematic review" "Cannabis-based products for pediatric epilepsy: An updated systematic ..." "Update on Cannabidiol Clinical Toxicity and Adverse Effects: A ..." Living Systematic Review on Cannabis and Other Plant-Based … Systematic Review of Cannabidiol (CBD) in the Treatment of … CBD Systematic Review And Meta – Your Trusted Guide Biological effects of Cannabidiol on normal human healthy cell ... "Long-term Effects of Cannabis on the Brain: A Systematic Review" A Systematic Review and Meta-Analysis of the Haemodynamic Cannabidiol As a Novel Candidate Alcohol Use Disorder Pharmacotherapy ... "Background: Compelling evidence from preclinical and clinical studies supports the therapeutic role of cannabidiol (CBD) in several medical disorders. We reviewed the scientific evidence on CBD-related toxicity and adverse events (AEs) in 2019, at the beginning of the spike in clinical studies involving CBD. However, CBD safety remained uncertain. Objective: With the benefit …" "The therapeutic role of Cannabidiol in mental health: a systematic …" A systematic review of cannabidiol trials in neurodevelopmental ... Evaluation of the potential use of cannabidiol in the treatment of ... "The Use of Cannabidiol in Treating Psychiatric Disorders: A Systematic ..." "Medical cannabinoids: a pharmacology-based systematic review …" "Cannabinoids for Medical Use: A Systematic Review and Meta-analysis ..." "Review Cannabis and orofacial pain: a systematic review" "The impact of THC and CBD in schizophrenia: A systematic review." "The Impact of THC and CBD in Schizophrenia: A Systematic Review" "The Impact of THC and CBD in Schizophrenia: A Systematic Review" "Adverse effects of cannabidiol: a systematic review and meta ... - Nature" "Potential Role of Cannabidiol on Sports Recovery: A Narrative Review" "Efficacy, Safety, and Regulation of Cannabidiol on Chronic Pain: A ..." "Immunomodulatory Potential of Cannabidiol in Multiple Sclerosis: …" Scientific Review Finds CBD Is 'Promising' Depression Treatment "Cannabidiol and Intestinal Motility: a Systematic Review - PMC" Use of cannabidiol in anxiety and anxiety-related disorders "The use of cannabinoids in children with epilepsy: A systematic review" Executive Summary - Living Systematic Review on Cannabis and Other ... "Cannabidiol (CBD): A Systematic Review of Clinical and …" "Pharmaceuticals | Free Full-Text | Cannabidiol (CBD): A Systematic ..." "Adverse effects of cannabidiol: a systematic review and meta" "Update on cannabidiol clinical toxicity and adverse effects: A ..." "Update on cannabidiol clinical toxicity and adverse effects: A ..." "Medical cannabis and mental health: A guided systematic review" A systematic review of cannabidiol dosing in clinical populations "Use of Cannabidiol in the Management of Insomnia: A Systematic Review" "Three studies had concomitant disease symptoms that were ameliorated (Table 2), suggesting that the transdermal formulations may have had some benefit.24,27,28 One study found superior absorption of CBDacid,23 the …" "The Impact of Cannabidiol on Human Brain Function: A Systematic Review" Therapeutic potential of minor cannabinoids in psychiatric … "Harnessing CBD for Athletic Excellence: Insights from a Systematic Review" A Systematic Review on the Pharmacokinetics of Cannabidiol in … "Covidence systematic review software was used. Tabulation, integration, and results: Fifty-nine studies were considered for full review, and 16 met inclusion criteria. Prevalence of cannabis use ranged from 13% to 27%. Most women ingested or inhaled cannabis and used cannabis multiple times per week, with dosages of THC and CBD up to 70 mg and ..." Use of cannabidiol in anxiety and anxiety-related disorders Efficacy and safety of cannabidiol for the treatment of canine ... How does cannabidiol (CBD) influence the acute effects of delta-9 ... The Evolving Role of Cannabidiol-Rich Cannabis in People with ... - MDPI "Cannabidiol (CBD) use in psychiatric disorders: A systematic review" "Cannabinoid therapies in the management of sleep disorders: A ..." "Cannabidiol (CBD): A Systematic Review of Clinical and …" "Cannabidiol in the context of substance use disorder treatment: A ..." "Efficacy, Safety, and Regulation of Cannabidiol on Chronic" "This review aimed to investigate what doses have been applied in clinical populations, in order to understand the active range of CBD in a variety of medical contexts. Methods: Publications …" "Cannabidiol in the context of substance use disorder treatment: A ..." Review article Cannabidiol for the treatment of psychosis among ... "The therapeutic role of Cannabidiol in mental health: a systematic review" A systematic review of cannabidiol trials in neurodevelopmental ... The Potential of Cannabidiol as a Treatment for Psychosis and Addiction ... "The Impact of THC and CBD in Schizophrenia: A Systematic Review" "Cannabinoid therapies in the management of sleep disorders: A ..." "Cannabidiol (CBD): A Systematic Review of Clinical and Preclinical ..." "Efficacy, Safety, and Regulation of Cannabidiol on Chronic Pain: …" "Effects of Cannabidiol on Appetite and Body Weight: A Systematic Review" "Update on cannabidiol clinical toxicity and adverse effects: A ..." Biological effects of Cannabidiol on normal human healthy cell ... "Cannabis-based products for pediatric epilepsy: An updated systematic ..." "Cannabidiol and Intestinal Motility: a Systematic Review - PMC" "Efficacy, Safety, and Regulation of Cannabidiol on Chronic Pain: A ..." "Cannabidiol as an Intervention for Addictive Behaviors: A Systematic ..." "One systematic review investigating whether CBD has antipsychotic effects found that CBD may offset the psychosis-like effects of THC (Iseger and Bossong, 2015). Although several narrative reviews have discussed the question of whether CBD interacts with THC when administered together acutely, this question has never been reviewed systematically." "Medical Cannabis for Gynecologic Pain Conditions: A Systematic Review" "Effectiveness of Cannabidiol to Manage Chronic Pain: A Systematic Review" "Cannabinoids for Medical Use: A Systematic Review and Meta …" "Food Effects on the Formulation, Dosing, and Administration of ..." "Adverse effects of cannabidiol: a systematic review and meta ... - PubMed" "Systematic Review on Transdermal/Topical Cannabidiol Trials: A …" The current review provides a systematic literature overview of studies that investigated the acute effects of CBD on the human brain of healthy volunteers and individuals diagnosed with a … "Effectiveness of Cannabidiol to Manage Chronic Pain: A …" "Anxiolytic effects of endocannabinoid enhancing compounds: A systematic ..." Cannabidiol as a Novel Candidate Alcohol Use Disorder A systematic review of cannabidiol dosing in clinical populations "Adverse effects of cannabidiol: a systematic review and meta ... - PubMed" "Medical Cannabis for Gynecologic Pain Conditions: A Systematic Review" "Adverse Effects of Oral Cannabidiol: An Updated Systematic …" "The therapeutic role of Cannabidiol in mental health: a …" "Immunomodulatory Potential of Cannabidiol in Multiple Sclerosis: a ..." Systematic literature review of human studies assessing the … "Particularly, cannabidiol has demonstrated analgesic and non-psychoactive properties. The objective of this systematic review is to update and to gather the clinical and preclinical …" Executive Summary - Living Systematic Review on Cannabis and … A systematic review of cannabidiol dosing in clinical populations Living Systematic Review on Cannabis and Other Plant-Based Treatments ... "Dosage, Efficacy and Safety of Cannabidiol Administration in …" "Psychiatric symptoms caused by cannabis constituents: a systematic ..." "Use of Cannabidiol in the Management of Insomnia: A Systematic Review" "Cannabidiol-associated hepatotoxicity: A systematic review and …" The Evolving Role of Cannabidiol-Rich Cannabis in People with … "Another systematic review examining medical use of CBD therapy in 12 RCTs found that the most common side effects included gastrointestinal symptoms (59.5%), somnolence (16.7%), loss of appetite (16.5%), and hypertransaminasemia (ALT/AST) (12.8%) with statistical analysis revealing significance (p ≤ 0.05) in using CBD for the increase in ..." "In this systematic review, we retrieved and critically evaluated available evidence regarding the immune and disease-modifying effects of CBD in experimental autoimmune encephalomyelitis (EAE) and in MS. Evidence in rodent models of EAE strongly supports CBD as effective, while clinical evidence is still limited and usually negative, due to ..." "Use of Cannabidiol in the Management of Insomnia: A Systematic Review" "Cannabinoid treatments for anxiety: A systematic review and ..." Living Systematic Review on Cannabis and Other Plant-Based … Executive Summary - Living Systematic Review on Cannabis … A systematic review of the antipsychotic properties of ... - PubMed "Adverse effects of cannabidiol: a systematic review and meta" "The therapeutic role of Cannabidiol in mental health: a systematic review" "CBD also has an impact on pain and exhibits anti-inflammatory properties. 9 Medical cannabis can be administered through many modalities, including oral or rectal capsules, transdermal patches, ... this is the first systematic review of the effect of the medicinal use of cannabis-based products for orofacial pain and inflammation. The use of ..." "Cannabidiol (CBD) use in psychiatric disorders: A systematic review" "Cannabidiol (CBD): A Systematic Review of Clinical and …" "Cannabidiol (CBD): A Systematic Review of Clinical and …" "Effectiveness of Cannabidiol to Manage Chronic Pain: A Systematic Review" "We conducted a systematic review to determine the efficacy and safety of cannabidiol (CBD) for chronic pain. The systematic review is according to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020 checklist. Five databases (PubMed, PubMed Central, Medline, Cochrane …" Adverse Events of Cannabidiol Use in Patients With Epilepsy "Effectiveness of Cannabidiol to Manage Chronic Pain: A Systematic Review" "Dosage, Efficacy and Safety of Cannabidiol Administration in …" "Dosage, Efficacy and Safety of Cannabidiol Administration in …" "CBD is a non-psychoactive component of the cannabis plant that has been shown to offer some benefits for people suffering from chronic pain, including arthritis and other joint and muscle pain. However, it is important to remember that this is still a new field and it is essential for healthcare professionals to take caution in prescribing it." "In this umbrella review of meta-analyses and systematic reviews, CBD use in epileptic patients was linked to an increased risk of ample AEs. Further research, specifically targeting various epilepsy categories, is essential to fully understand the effectiveness and potential side effects of CBD across different epilepsy forms." Cannabidiol (CBD) in the Management of Schizophrenia "Anticoagulant drug-drug interactions with cannabinoids: A systematic review" "Highly Purified Cannabidiol for Epilepsy Treatment: A Systematic Review ..." "As a non-psychoactive element of the cannabis plant, CBD has received much attention due to the potential role it may play in mood disorder management. This article aims to conduct a thorough systematic review of existing studies on CBD treatment for mood disorders focused in investigating the safety and effectiveness of the product." "The Impact of Cannabidiol on Human Brain Function: A Systematic Review" "Cannabis-Based Products for Chronic Pain : A Systematic Review" "Cannabidiol (CBD): A Systematic Review of Clinical …" "Efficacy, Safety, and Regulation of Cannabidiol on Chronic Pain: …" The Potential of Cannabidiol as a Treatment for Psychosis and Addiction ... "Adverse effects of cannabidiol: a systematic review and meta-analysis ..." "In this review, we describe emergent cannabis product chemotypes (e.g. THC-dominant, CBD-dominant, balanced or ‘hybrid’ with high concentrations of THC and CBD), product formulations (e.g. edibles, concentrates), and methods of administration (e.g. smoked, vaporized, orally ingested)." "Cannabidiol (CBD) use in psychiatric disorders: A systematic review" "Introduction: This systematic review aimed to assess efficacy and safety for skin-applied formulations containing CBD.Methods: Bibliographic and clinical trial registries were searched for interventional human trials using cutaneously administered CBD or reported plasma CBD concentrations (any species).Results: Eight of 544 articles fitted the selection criteria: 3 …" "Cannabidiol in the context of substance use disorder treatment: A ..." "Cannabis for Chronic Pain: Mechanistic Insights and Therapeutic …" "Cannabinoids for the Treatment of Hair, Scalp, and Skin …" Use of Medicinal Cannabis and Synthetic Cannabinoids in Post … Exploring the efficacy and safety of cannabidiol in ... - Springer "Cannabidiol (CBD): A Systematic Review of Clinical and …" "The Impact of THC and CBD in Schizophrenia: A Systematic Review" "Cannabidiol (CBD): A Systematic Review of Clinical and ... - MDPI" "Potential Role of Cannabidiol on Sports Recovery: A Narrative Review" "The therapeutic role of Cannabidiol in mental health: a …" "Adjunctive CBD in patients with LGS or DS experiencing seizures uncontrolled by concomitant anti-epileptic treatment regimens is associated with a greater reduction in seizure frequency and a higher rate of AEs than placebo. ... A Systematic Review and Meta-Analysis Drugs. 2018 Nov;78(17):1791-1804. doi: 10.1007/s40265-018-0992-5. ..." "Adverse effects of cannabidiol: a systematic review and meta …" "The Impact of Cannabidiol on Human Brain Function: A …" "Cannabidiol (CBD): A Systematic Review of Clinical and …" Cannabinoids for the treatment of mental disorders and … Cannabidiol as a Novel Candidate Alcohol Use Disorder ... - PubMed "Therapeutic potential of cannabidiol (CBD) in anxiety disorders: A ..." "Use of Cannabidiol in the Management of Insomnia: A Systematic Review" "The Impact of THC and CBD in Schizophrenia: A Systematic Review" Cannabidiol in humans-the quest for therapeutic targets Cannabis-Induced Gastrointestinal Tract Symptoms in the Adult ... "Cannabidiol (CBD) use in psychiatric disorders: A systematic review" "Cannabidiol in the context of substance use disorder treatment: A ..."

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